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胰腺癌术后辅助化疗价值的Meta分析
引用本文:温景芸,陈洁,林曲,董敏,吴祥元.胰腺癌术后辅助化疗价值的Meta分析[J].中国误诊学杂志,2011,11(13):3027-3029.
作者姓名:温景芸  陈洁  林曲  董敏  吴祥元
作者单位:中山大学附属第三医院肿瘤内科,广东,广州,516000
摘    要:目的通过Meta分析评价术后辅助化疗在胰腺癌治疗中的价值。方法按入选标准,检索CBMDisc、CNKI和PubMed数据库收集有关胰腺癌根治性术合并术后辅助化疗与单纯根治性手术的随机临床对照研究的文献。运用Review Manager 4.2软件对数据进行Meta分析。结果共6篇文献入选,累计病例共1 069例。与单纯手术组相比,胰腺癌术后合并术后辅助化疗患者5 a生存率优势比OR=1.55,P=0.15,95%置信区间为0.85~2.83。结论根据目前资料,胰腺癌术后辅助化疗,未能改善5 a生存率。

关 键 词:胰腺肿瘤/外科学  肿瘤辅助疗法  Meta分析

Meta-analysis of postoperative adjuvant chemotherapy for patients with radical surgery of pancreatic cancer
WEN Jing-yun,CHEN Jie,LIN Qu,DONG Min,WU Xiang-yuan.Meta-analysis of postoperative adjuvant chemotherapy for patients with radical surgery of pancreatic cancer[J].Chinese Journal of Misdiagnostics,2011,11(13):3027-3029.
Authors:WEN Jing-yun  CHEN Jie  LIN Qu  DONG Min  WU Xiang-yuan
Institution:WEN Jing-yun,CHEN Jie,LIN Qu,DONG Min,WU Xiang-yuan Department of Medical Oncology,The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou 516000,China
Abstract:Objective To evaluate the efficacy of adjuvant chemotherapy in patients with pancreatic cancer after radical surgery.Methods Randomized clinical studies of surgery plus postoperative adjuvant chemotherapy and surgery alone for patients with radical surgery of pancreatic cancer were selected from CBMdisc,CNKI,and PubMed databases.RevMan4.2 software was used for meta-analysis.Results Six reports were included in the meta-analysis and a total of 1 069 patients had been included.Compared with that of the patien...
Keywords:Pancreatic Neoplasms/surgery  Neoadjuvant Therapy  Meta-Analysis  
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