| HIFU技术中的超声空化及空化增强效应研究进展 |
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| 引用本文： | 任小龙 综述,周晓东 审校.HIFU技术中的超声空化及空化增强效应研究进展[J].中国医学影像技术,2006,22(2):310-312. |
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| 作者姓名： | 任小龙 综述 周晓东 审校 |
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| 作者单位： | 第四军医大学西京医院超声科,陕西西安,710032 |
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| 基金项目： | 国家自然科学基金资助项目(30570489)。 |
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| 摘 要： | 超声空化效应是高强度聚焦超声(HIFU)治疗中的重要效应之一,有效诱导并且利用超声空化效应可以增加HIFU辐照后的组织凝固范围和提高HIFU疗效。微泡造影剂被确认为是提高HIFU疗效的一种重要增效剂,其作用就是作为超声空化效应的空化核,降低聚焦超声对组织的损伤阈值从而可以扩大组织的凝固范围。随着对HIFU增效作用的研究进展,HIFU技术必将更加高效、安全,成为临床治疗肿瘤的有力武器。
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| 关 键 词： | 高强度聚焦超声 造影剂 微泡 空化效应 图像增强 |
| 文章编号： | 1003-3289（2006）02-0310-03 |
| 收稿时间： | 2005-07-10 |
| 修稿时间： | 2005-10-10 |
Progress of ultrasonic cavitation and cavitation-induced enhancement effectin high intensity focused ultrasound |
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| REN Xiao-long and ZHOU Xiao-dong.Progress of ultrasonic cavitation and cavitation-induced enhancement effectin high intensity focused ultrasound[J].Chinese Journal of Medical Imaging Technology,2006,22(2):310-312. |
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| Authors: | REN Xiao-long and ZHOU Xiao-dong |
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| Institution: | Department of Ultrasound , Xijing Hospital ,the Fourth Military Medical University , X I'an 710032 , China;Department of Ultrasound , Xijing Hospital ,the Fourth Military Medical University , X I'an 710032 , China |
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| Abstract: | Ultrasonic cavitation is one of predominant mechanisms in high intensity focused ultrasound (HIFU) treatment. Efficiently-induced ultrasonic cavitation can be used to increase the coagulated volume and enhance the therapeutic efficiency of HIFU. Recent studies have shown that microbubble contrast agents are important factors in enhancing the therapeutic efficiency of HIFU. They have potential to act as cavitation nuclei and are likely to lower the tissue damage threshold and cause a greater coagulated volume.Along with the development of HIFU efficiency enhancement studies, HIFU will be more effective and powerful in clinical tumor treatment. |
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| Keywords: | High intensity focused ultrasound Contrast media microbubbles Cavitation Image enhancement |
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