| 克山病心肌蜡块标本的肠道病毒RNA检测 |
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| 引用本文： | 李延文,杨英珍.克山病心肌蜡块标本的肠道病毒RNA检测[J].中华医学杂志,1995,75(6):340-345. |
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| 作者姓名： | 李延文 杨英珍 |
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| 作者单位： | 上海市心血管病研究所，上海医科大学中山医院，上海医科大学病理学教研室，云南省楚雄克山病防治研究中心 |
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| 摘 要： | 为探讨肠道病毒染与克山病的关系，用套式聚合酶链反应分别对２１例楚雄地区克山病尸检心肌及２１例脑外伤尸检心肌的蜡块标本进行了肠道病毒ＲＮＡ检测。发现１８例克山病心肌标本中有肠道病毒ＲＮＡ存在，阳性率高达８５．７％，而脑外伤心示本均为阴性。
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| 关 键 词： | 心肌病 柯萨奇病毒 感染 聚合酶链反应 |
Detection of enteroviral RNA in Paraffin-emheddedmyocardial tissue froni patieuts with Keskan
by uestedPCR |
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| Li Yanwen, Yang Yingzhen , Chen Haozhu,et al..Detection of enteroviral RNA in Paraffin-emheddedmyocardial tissue froni patieuts with Keskan
by uestedPCR[J].National Medical Journal of China,1995,75(6):340-345. |
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| Authors: | Li Yanwen Yang Yingzhen Chen Haozhu |
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| Abstract: | nteroviral RNA in paraffinembedded myocardialspecimens from 21
patients with Keshan disease and 21patients with cerebral trauma was investigated by
nestetlpolymerase chain reaction. Of the 21 patients with Ke-shan Disease, 18 (85. 7%) showed
positive findings.Their myocardial tissues were infected by enteroviruspreviously. The results
suggest that enterovirus infec-tion is the major cause of Keshan disease in the Chux-iong
district, Yunnan province. |
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| Keywords: | Myocardial diseases Coxsack-ievirus infections Polymerase chain reaction |
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