| 帕金森病患者嗅觉障碍的临床研究 |
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| 引用本文： | 彭蓉,张锦红,吴妍,陈文军,刘鸣,袁光固. 帕金森病患者嗅觉障碍的临床研究[J]. 现代预防医学, 2007, 34(1): 173-174,181 |
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| 作者姓名： | 彭蓉 张锦红 吴妍 陈文军 刘鸣 袁光固 |
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| 作者单位： | 四川大学华西医院神经内科,成都,610041 |
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| 摘 要： | [目的]检测帕金森病患者的嗅觉功能，初步探讨帕金森病的嗅觉改变情况及临床意义。[方法]收集105例PD患者和105例年龄、性别与之相匹配的健康成人作对照，分别进行简易嗅觉检查。并按性别、年龄、病程、Hoehn-Yahr分级进行统计学分析。[结果]PD患者的嗅觉障碍发生率．（95．5％）远高于对照组（48．6％），OR值9．048，差异有统计学意义；运动症状出现以前12％的PD患者存在嗅觉障碍。[结论]PD患者存在明显嗅觉障碍。在病程早期及运动症状出现前即可存在.
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| 关 键 词： | 帕金森病 嗅觉障碍 |
| 文章编号： | 1003-8507（2007）01-0173-02 |
| 收稿时间： | 2006-09-28 |
| 修稿时间： | 2006-09-28 |
RESEARCH ON DYSOSMIA IN PATIENTS WITH PARKINSON''''S DISEASE |
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| PENG Rong, ZHANG Jin-hong, WU Yan,et al.. RESEARCH ON DYSOSMIA IN PATIENTS WITH PARKINSON''''S DISEASE[J]. Modern Preventive Medicine, 2007, 34(1): 173-174,181 |
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| Authors: | PENG Rong ZHANG Jin-hong WU Yan et al. |
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| Affiliation: | Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041 |
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| Abstract: | [Objective]To detect the olfactory function in patients with Parkinson's disease(PD)and explore the clinical significance.[Methods]Olfaction was examined in 105 PD patients and in 105 healthy controls well matched for sex,age and education,statistics analysis was employed according to sex,age,duration,and Hoehn-Yahr degree.[Results]The incidence of dysosmia in PD patients(95.5%)was significantly higher than that in the healthy controls(48.6%)(P = 0.000).12% of PD patients had dysosmia before motor symptoms appeared.[Conclusions]The olfactory function decreases significantly in PD patients and probably appears in the early stage. |
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| Keywords: | Parkinson's disease Dysosmia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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