Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes |
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| Authors: | A. Willcox S. J. Richardson A. J. Bone A. K. Foulis N. G. Morgan |
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| Affiliation: | (1) Institute of Biomedical and Clinical Science, Peninsula College of Medicine and Dentistry (University of Exeter), Tamar Science Park, Derriford, Plymouth, PL6 8BU, UK;(2) Institute of Biomedical and Clinical Science, Peninsula College of Medicine and Dentistry (University of Plymouth), Plymouth, UK;(3) School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK;(4) Department of Pathology, Glasgow Royal Infirmary, Glasgow, UK; |
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| Abstract: | Aims/hypothesis In adults, the rate of beta cell replication is normally very low, but recent evidence suggests that it may increase during insulitis. We therefore studied tissue from donors with recent-onset type 1 diabetes to establish whether islet cell proliferation is increased during the disease process. |
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