| 透明质酸钠关节腔内注射致过敏反应 |
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| 引用本文： | 廖淑梅,南玲. 透明质酸钠关节腔内注射致过敏反应[J]. 药物不良反应杂志, 2011, 13(1): 49-49 |
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| 作者姓名： | 廖淑梅 南玲 |
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| 作者单位： | 第三军医大学大坪医院野战外科研究所关节四肢外科,重庆,400042 |
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| 摘 要： | 1例71岁男性患者因膝关节骨性关节炎入院给予透明质酸钠20 mg右膝关节腔内注射。第1次治疗后患者无明显不适。6 d后,第2次膝关节腔内注射透明质酸钠20 mg。注射后约5 h,患者突然出现寒战、心慌、呼吸困难,血压96/60 mm Hg(1 mmHg=0.133 kPa)。立即给予吸氧等对症治疗,1 h后症状逐渐缓解,血压105/70 mm Hg。住院期间未再应用该药,未再发生上述不良反应。共住院2周出院。
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| 关 键 词： | 透明质酸钠 过敏反应 |
Anaphylactic reactions caused by intra-articular injection of sodium hyaluronate |
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| Liao Shumei,Nan Ling. Anaphylactic reactions caused by intra-articular injection of sodium hyaluronate[J]. Adverse Drug Reactions Journal, 2011, 13(1): 49-49 |
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| Authors: | Liao Shumei Nan Ling |
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| Affiliation: | Liao Shumei,Nan Ling (Department of Joint and Orthopedic Surgery,Daping Hospital,Third Military Medical University,Chongqing 400042,China) |
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| Abstract: | A 71-year-old man with knee osteoarthritis was given an intra-articular injection of sodium hyaluronate 20 mg in his right knee.The patient did not present with obvious discomfort after the first injection.Six days later,he received the second intra-articular injection of sodium hyaluronate 20 mg.About 5 hours after the second injection,he experienced chills,palpitation,and dyspnea.At the same time,his blood pressure was 96/60 mm Hg.He received oxygen inhalation therapy and symptomatic treatment.One hour la... |
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| Keywords: | sodium hyaluronate anaphylactic reactions |
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