| 13C-呼气试验评估胰腺外分泌功能的临床应用 |
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| 引用本文： | 蔡铭慈,陈志威,曲新华,黄晓璐,严惟力,黄钢. 13C-呼气试验评估胰腺外分泌功能的临床应用[J]. 胃肠病学, 2009, 14(5): 307-309. DOI: 10.3969/j.issn.1008-7125.2009.05.014 |
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| 作者姓名： | 蔡铭慈 陈志威 曲新华 黄晓璐 严惟力 黄钢 |
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| 作者单位： | 上海交通大学医学院附属仁济医院核医学科,上海交通大学医学院临床核医学研究所,200127 |
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| 基金项目： | 国家自然科学基金，卫生部卫生公益性行业科研专项经费项目，中国博士后科学基金 |
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| 摘 要： | 三酰甘油、蛋白质和淀粉均可作为13C-呼气试验的底物，用于检测胰腺外分泌功能。目前研究最多的是13C-三酰甘油呼气试验，其中以13C-混合三酰甘油呼气试验（MTG—BT）最具优势。N-苯甲酰-L-酪胺酰-【1-13C】丙氨酸（Bz—Tyr—Ala）呼气试验无需试餐，近年逐渐受到关注。13C-淀粉呼气试验影响因素较多，研究近况不甚理想。本文对各类，13C-呼气试验的底物特点及其评估胰腺外分泌功能的临床应用作一综述。
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| 关 键 词： | 碳同位素 呼气试验 胰腺外分泌功能不全 方法学 |
Clinical Application of 13C-Breath Test in Assessment of Pancreatic Exocrine Function |
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| CAI Mingci,CHEN Zhiwei,Qu Xinhua,HUANG Xiaolu,YAN Weili,HUANG Gang. Clinical Application of 13C-Breath Test in Assessment of Pancreatic Exocrine Function[J]. Chinese Journal of Gastroenterology, 2009, 14(5): 307-309. DOI: 10.3969/j.issn.1008-7125.2009.05.014 |
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| Authors: | CAI Mingci CHEN Zhiwei Qu Xinhua HUANG Xiaolu YAN Weili HUANG Gang |
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| Affiliation: | CAI Mingci, CHEN Zhiwei, QU Xinhua, HUANG Xiaolu, YAN Weili, HUANG Gang. (Department of Nuclear Medicine, Renji Hospital, Shanghai Jiaotong University School of Medicine; Institute of Clinical Nuclear Medicine, Shanghai Jiaotong University School of Medicine, Shanghai (200127) |
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| Abstract: | Triglyceride, protein and starch can be used as substrate of 13C-breath test to evaluate the pancreatic exocrine function. 13C-triglyceride breath test is most commonly used at present, and 13C-mixed triglyeeride breath test （MTG-BT） has the greatest advantage. N-benzoyl-L-tyrosyl-[1-13C]alanine （Bz-Tyr-Ala） breath test needs no test meal, which makes it more interested. Meanwhile, because of the existence of many influencing factors, the study on 13C-starch breath test is not ideal. This article reviewed the use of different substrates in 13C-breath tests and their clinical application in evaluating pancreatic exocrine function. |
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| Keywords: | Carbon Isotopes Breath Tests Exocrine Pancreatic Insufficiency Methodology |
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