胶原贴敷料联合面部外治法治疗寻常险匮唐蝴析

目的观察胶原贴敷料联合面部外治法治疗寻常型痤疮的疗效和安全性。方法将150例寻常型痤疮患者随机分成两组，治疗组75例，对照组75例。治疗组和对照组均给予面部外治法，每周1次，同时予罗红霉素缓释胶囊0．3g，qd，VI服；甲硝唑0．2g，Bid，口服，治疗组同时给予胶原贴敷料每晚1次，连用1周，然后改为隔日1次，疗程共8周。于治疗前、治疗4周、治疗8周分别观察患者的皮损情况、色素沉着情况、皮脂溢出情况及不良反应。结果治疗组有效率为95．83％，对照组94．66％，皮损综合情况疗效比较差异无统计学意义，但是，治疗后皮脂溢出情况、色素沉着情况较对照组差异有统计学意义，两组均未见明显不良反应。结论胶原贴敷料苷联合面部外治法治疗寻常型错痤疮疗效好、安全。且胶原贴敷料能明显改善面部油脂溢出和面部痤疮后色素沉着。

Effect observation of collagen dressing combined with facial external treatment on acne vulgaris

Objective To observe the efficacy and safety of compound collagen dressing combined with facial external ues in the treatment of ache vulgaris. Methods 150 cases with acne vulgaris were divided into two groups randomly. Patients in the treatment group and the control group were given facial external treatment once a week and compound roxithromycin, 0.3g, Po, Qd, metronidazole,0.2g,Po,Bid. At the same time, the patients in the treatment group were given collagen dressing one piece every night for 1 week. Then, the dosage was reduced to one piece every other night for 3 weeks. Results The response rates were 95.83% and 94.66% respectively. There was no significant difference between the treatment group and the control group. But the rate of seborrhea and pigment fade was significant difference between the treatment group and the control group after the treatment of collagen dressing. No significant adverse events were found. Conclusion Compound collagen dressing combined with facial external treatment is effective and safe in the treatment of acne vulgaris. Sebum overflow reduce and the extinction of pigment expedite after treated in combination with dressing collagen.