生物纸在重度慢性阻塞性肺疾病患者电视胸腔镜肺切除术中应用的效果分析

目的 探讨大清生物纸（可吸收止血膜）应用于重度慢性阻塞性肺疾病（COPD）患者电视胸腔镜肺切除术（VATS）中的疗效.方法 重度COPD患者在VATS使用直线型切割缝合器后,分为使用大清生物纸48例（大清组）和不使用大清生物纸37例（对照组）.比较两组患者术后平均漏气时间、渗血情况及平均住院时间.结果 两组患者术后均未出现需要机械辅助通气现象,无手术死亡病例.大清组术后平均住院时间为（7.8±2.1）d,术后平均漏气时间为（3.3±2.1）d;对照组术后平均住院时间为（9.8±3.4）d,术后平均漏气时间为（5.0±3.2）d.两组患者术后住院时间、术后漏气时间之间差异均有统计学意义（P＜0.05）.结论 应用大清生物纸行肺创面加强修补,可有效预防重度COPD患者肺切除术后肺漏气和渗血等并发症,减少了患者的术后住院时间,大大减轻了患者的痛苦及经济负担.

The clinical efficacy of bio-paper in VATS lobectomy for patients with severe chronic obstructive pulmonary disease

Objective To investigate the clinical efficacy of bio-paper in video-assisted thoraco- scopic surgery（VATS） lobectomy for patients with severe chronic obstructive pulmonary disease （COPD）. Methods During the VATS lobectomy for COPD,48 patients were applied with bio-paper after the appli- cation of linear cut stapler（ the bio-paper group） ,and the other 37 patients who were not treated with bio- paper were enrolled as control（ the control group）. Postoperative hospitalization time,air leakage time and bleeding condition were compared between the groups. Results There was no postoperative mechanical ventilation and death. In the bio-paper group, the average postoperative hospitalization time was 7.8 ＋ 2.1 days and the average postoperative pulmonary air leak time was 3.3 ~ 2.1 days ; in the control group, the average postoperative hospitalization time was 9.8 ~ 3.4 days and the average pulmonary air leak time was 5.0 ~ 3.2 days. There were significant differences in postoperative hospitalization time and pulmonary leakage time between the two groups （ P = 0. 001 and 0. 004, respectively）. Conclusion The bio-paper can reinforce the pulmonary wound repair and effectively reduce complication such as postoperative pulmo- nary air leaks and bleeding. It saves hospitalization time, which may greatly reduce the patient g suffering and economic burden.