陕西省克山病病区粮食和人群硒水平调查

目的了解陕西省克山病病区粮食和人群硒水平。方法按整群分层抽样的方法,于2006-2007年,在陕西省克山病区范围内抽取6个病区县（区）的12个自然村作为调查点,采集调查点居民户自产主食粮食小麦和玉米515份,克山病患者和病区健康人发样307份、全血248份及非病区健康人血样64份,用2,3-二氨基萘荧光法、原子荧光法和化学比色法分别测定粮食、发硒、全血硒含量和谷胱甘肽过氧化物酶（GSH-Px）活力。结果病区居民粮食（小麦、玉米）硒含量为（0.045±0.036）和（0.035±0.025）mg/kg,克山病患者发硒含量（0.376±0.091）mg/kg低于病区健康人（0.384±0.077）mg/kg,差异无统计学意义（P〉0.05）;克山病患者全血硒含量（0.071±0.017）mg/L低于病区健康人（0.077±0.017）mg/L,差异有统计学意义（P〈0.05）,病区健康人明显低于非病区健康人（0.090±0.016）mg/L,差异有统计学意义（P〈0.01）;克山病患者GSH-Px（75.16±12.10）U/L低于病区健康人（85.70±14.66）U/L,差异有统计学意义（P〈0.05）。结论病区粮食和人群硒水平明显升高,与生活水平的提高和膳食结构的明显改善有关。

Investigation on Selenium levels of food supplies and people in Keshan disease area of Shaanxi Province

Objective To understand selenium levels of food supplies and people in Keshan disease area of Shaanxi province.Methods From 2006 to 2007,througn stratified cluster sampling,12 villages from 6 endemic counties were randomly selected as investigation points.307 hair samples and 248 whole blood samples from the Keshan patients and healthy people from the same districts,as well as 64 blood samples from other counties were collected and detected by Diaminonaphthalene fluorometric method,Atomic-Fluorescence Spect...