无偿献血人群戊型肝炎病毒感染情况调查

目的调查绍兴市街头无偿献血者戊型肝炎病毒感染情况。方法3701例无偿献血者标本采用ELISA方法检测抗-HEV IgG和抗-HEV IgM,RT-PCR检测抗-HEV IgM阳性血清HEV RNA。结果本市无偿献血者抗-HEV IgG阳性率为29.91%(1107/3701);抗-HEVIgM阳性率为1.35%(50/3701);HEV RNA阳性6例,检出率为0.16%(6/3701),均为HEV基因1型;各季节抗-HEV IgG和抗-HEV IgM的阳性检出率无显著差异。结论加强对献血者感染HEV情况的检测和研究,对保证用血安全,完善安全输血的保障体系有切实的意义。

Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing

Objective To investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing. Methods Blood specimes from 3701 non-remunerate blood donors were collected,ELISA were used to study anti-HEV IgG and IgM antibodies,RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.Results Anti-HEV IgG positive rate was 29.19%(1107/3701),anti-HEV IgM positive rate was 1.35%(50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701) ,and all the 6 cases belonged to HEV geno type 1. Different seasons showed no interference on the positive rate of IgG and IgM.Conclusion The detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.