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川芎中多糖的研究
引用本文:范智超,张志琪. 川芎中多糖的研究[J]. 中草药, 2006, 37(7): 973-976
作者姓名:范智超  张志琪
作者单位:陕西师范大学,药用植物资源与天然药物化学教育部重点实验室,陕西,西安,710062
基金项目:国家自然科学基金资助项目(20175012)
摘    要:目的研究川芎L igusticum chuanx iong干燥根茎中的多糖组分。方法采用DEAE-纤维素柱色谱和凝胶渗透色谱分离纯化,化学和光谱方法分析其结构特征。结果从川芎水提物中分级得到4个均一多糖组分LCP-1、LCP-2、LCP-3和LCP-4,其相对分子质量分别为3.1×104、5.2×104、9.0×104、3.6×104,四者均为结构复杂的多糖组分。结论首次从川芎中分离得到LCP-1、LCP-2、LCP-3和LCP-4 4种杂多糖。

关 键 词:川芎  多糖  结构分析
文章编号:0253-2670(2006)07-0973-04
收稿时间:2005-11-01
修稿时间:2005-11-01

Polysaccharides from Ligusticum chuanxiong
FAN Zhi-chao and ZHANG Zhi-qi. Polysaccharides from Ligusticum chuanxiong[J]. Chinese Traditional and Herbal Drugs, 2006, 37(7): 973-976
Authors:FAN Zhi-chao and ZHANG Zhi-qi
Affiliation:Key Laboratory of Medicinal Plant Resource and Natural Pharmaceutical Chemistry of Ministry of Education, Shaanxi Normal University, Xi'an 710062, China;Key Laboratory of Medicinal Plant Resource and Natural Pharmaceutical Chemistry of Ministry of Education, Shaanxi Normal University, Xi'an 710062, China
Abstract:Objective To study the polysaccharides from dried rhizome of Ligusticum chuanxiong. Methods DEAE-Cellulose and gel-filtration chromatography were used to isolate and purify the polysaccharides, whose structures were characterized by chemical and spectral methods. Results Four homogeneous polysaccharides, named LCP-1,LCP-2,LCP-3,and LCP-4 were obtained from the water extract of L.chuanxiong. Four structures were investigated to be complicated polysaccharied fractions,with the molecular weights of 3.1×104,5.2×104,9.0×104,and 3.6×104, respectively, then estimated by GPC. Conclusion The four polysaccharides are obtained from this plant for the first time.
Keywords:Ligusticum chuanxiong Hort.  polysaccharides  structural analysis
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