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Cellular reactions in a SRBC-induced inflammatory exudate
Authors:Charles E Slonecker
Abstract:Acute inflammatory exudates which are induced by the intra-peritoneal injection of sheep red blood cells contain a variety of connective tissue cell types. Granulocytes, macrophages and lymphocytes constitute the vast majority of the exudate cells. The peritoneal macrophages are principally involved in the phagocytosis and clearance of the whole SRBC from the peritoneal cavity. The exudate lymphocytes which accumulate during the first 24 hours are derived from a pool with a fast turnover rate and are newly formed. While these lymphocytes undergo an enlargement and increase their basophilic cytoplasm during this response, they fail to show increases in their DNA synthesis while in the inflammatory exudate.
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