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胃黏膜不典型增生患者血清胃泌素及生长激素的检测及意义
引用本文:郭振华,金建军.胃黏膜不典型增生患者血清胃泌素及生长激素的检测及意义[J].河南科技大学学报(医学版),2012,30(2):93-95.
作者姓名:郭振华  金建军
作者单位:河南科技大学第一附属医院,河南洛阳,471003
摘    要:目的探讨胃黏膜不典型增生患者血清胃泌素(GAS)及生长激素(GH)的检测及意义。方法收集胃黏膜不典型增生患者共90例,其中轻度不典型增生35例,中度不典型增生35例,重度不典型增生20例。测定均应用放射免疫法检测患者血清GAS及GH浓度。结果 GH及GAS在胃黏膜不典型增生患者血清中浓度升高,且随不典型增生的发展升高明显(P<0.05),在胃黏膜不典型增生患者的表达具有相关性(r=0.515)。结论联合检测GH及GAS对胃黏膜不典型增生发展预测及治疗指导有意义。

关 键 词:不典型增生  胃泌素  生长激素

Detection and Significance of Serum Gastrin and Growth Hormone in Patients with Gastric Mucosal Dysplasis
GUO Zhen-hua , JIN Jian-jun.Detection and Significance of Serum Gastrin and Growth Hormone in Patients with Gastric Mucosal Dysplasis[J].Journal of Henan University of Science & Technology:Medical Science,2012,30(2):93-95.
Authors:GUO Zhen-hua  JIN Jian-jun
Institution:(First Affiliated Hospital,Henan University of Science and Technology,Luoyang 471003,China)
Abstract:Objective To investigate the role of serum gastrin(GAS) and growth hormone(GH) in the patients with gastric mucosal dysplasis. Methods To collect 90 cases with gastric mucosal dysplasis including 35 cases of mild dysplasia,35 cases of moderate dysplasia and 20 cases of severe dysplasia.GAS and GH were detected by radioimmunoassy. Results GH and GAS in the gastric mucosal dysplasia with serum concentrations increased,and increased significantly with the development of dysplasia(P<0.05).There was positive correlation between the expression of serum GH and GAS in gastric membrane(r=0.515). Conclusion There is a guided significance for joint detection of GH and GAS meaningful forecasts and treatment of gastric mucosal dysplasia development.
Keywords:dysplasis  gastrin  growth hormone
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