神经妥乐平治疗腰椎间盘突出症患者疼痛及麻木症状的临床效果研究

目的：观察神经妥乐平治疗腰椎间盘突出症疼痛及麻木症状的疗效。方法门诊纳入影像学及临床表现可确诊为腰椎间盘突出症及视觉模拟评分法（visualanaloguescale，VAS）在5分以上的患者56例，分为甲钴胺组及神经妥乐平＋甲钴胺组。不使用其它药物及按摩针灸等治疗，并要求患者卧床休息。观察两组患者的疼痛及麻木缓解情况。结果服药后第1周及第2周两组间疼痛VAS评分差异有统计学意义，神经妥乐平＋甲钴胺组和甲钴胺组对疼痛缓解的显效率于第2周时分别为：62.5％，8.3％，有效率分别为75.0％，41.6％。两组对麻木症状的缓解差异无统计学意义。结论神经妥乐平联合甲钴胺对腰椎间盘突出症疼痛的缓解优于单独应用甲钴胺，而对于麻木的缓解两组间差异无统计学意义。

A clinical study of pain and numbness relief in the patients with lumbar disc herniation treated with neurotropin

Objective To verify the effects of neurotropin on the relief of pain and numbness in the patients with lumbar disc herniation. Methods A total of 56 patients who were diagnosed as lumbar disc herniation based on the imaging data and clinical manifestations in the clinic and whose VAS scores were more than 5 points were divided into 2 groups. The patients in one group were treated with methylcobalamin, and the patients in the other group was treated with neurotropin＋methylcobalamin. No other therapies such as medicine, massage or acupuncture were performed. All the patients were suggested to stay in bed. The relief of pain and numbness was observed in both groups. Results The differences of the VAS pain scores between the 2 groups were statistically signiifcant at the 1st and 2nd week after the medicines were taken. The excellent rates of pain relief in the neurtropin＋methylcobalamin group and the neurtropin group were 62.5%and 8.3%respectively at the 2nd week, and the effective rates were 75.0%and 41.6%respectively. The differences of the numbness relief between the 2 groups were not statistically signiifcant. Conclutions The joint application of neurtropin and methylcobalamin is superior to the single application of methylcobalamin for the relief of the pain in the patients with lumbar disc herniation. There are no statistically signiifcant differences between the 2 groups for the relief of numbness.
{URL}： http：//d.g.wanfangdata.com.cn/Periodical_zggzlzz201404009.aspx