沙市地区某些人群抗-HCV调查

用第二代抗－ＨＣＶ试剂检测沙市地区２０８４名献血员与８９０名肝病患者。结果献血员抗－ＨＣＶ阳性率为０．２９％，肝病患者为１．３５％，表明沙市地区存在ＨＣＶ感染，其感染率相对较低。４３２名甲肝与８名急性乙肝病人未检出阳性，而４４３名慢性乙肝中有１１例阳性，阳性率为２．４８％，５例肝硬化病人中有１例阳性。提示混合或重叠ＨＣＶ感染，对ＨＢＶ感染的慢性化、肝硬化起一定促进作用。最后作者慎重提出试验结果的假

Investigation on Anti-HCV Antibody in Shashi District

In Shashi District, 2084 blood donors and 890 patients with liver diseases have been tested for anti-HCV antibody by using the second generation reagent. As a result, the blood donors showed a positive rate of 0.29% and the patients with liver diseases 1.35%. This indicated that HCV virus infection was present in Shashi District, and the infection is relatively low. Positive result was not found among 432 patients with hepatitis A and 8 patients with actue hepatitis B, while 11 out of 443 patients with chronic hepatitis B showed positive result with a positive rate of 2.48%. One of five patients with active cirrhosis of liver was positive for anti-HCV antibody. It indicates that the mixed or cross HCV infection might lead to chronicity of the HCV infection and active cirrhosis.