胃癌亚类危险因子的流行病学研究——多组Logistic回归分析

根据胃癌发生阶段模式的认识，我们设计实施了一析的病例对照研究，分析方法采用多组Ｌｏｇｉｓｔｉｃ分析法，研究对象９为四组病例和一组对照，他们分别是胃癌组、重度异型增生组、慢性萎缩性胃炎伴肠化生组和溃汤病组以及对照组。对照组是病理证实胃粘膜正常或仅有轻度性慢浅表性胃患者。研究结果显示：胃癌的危险因素是长期居住在高发区，经济收低下，动物蛋白摄入量少，地瓜、墨鱼摄入量大，暴饮暴食和精神创伤。重度异增生的危

The Epidemiological Study of Subtype Risk Factors of Gastric Cancer

On the basis of understanding multistage pattern of the development of gastric cancer, we designed and carried out a new case-control study. The methods of analysis was multigroup logistic regression analysis. The studied objects were 4 groups of cases and 1 group of control. They were gastric Cancer group, severe dysplasia group, chronic atrophic gastritis accompanied by intestinal metaplasia group, ulcer group and control group, respectively. The control group was confirmed by pathology which showed that the gastric mucosa was normal or had sonly mild chronic superficial gastritis. The renlts showed that the risk factors of gastric cancer were living in high incidence area for a long period, low economic income, low animal protein intake, high sweet potato and inkfish ointake, ating and drinking too much at ne meal and mental injuring The risk factors of severe dysplasia were low intake of protein, intake of non-fresh fish, large intake of inkfish and salted meat, a family history of gastric cancer.