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外周血中血管内皮细胞数量与胶质瘤的关系
引用本文:郝继山,杨玉山.外周血中血管内皮细胞数量与胶质瘤的关系[J].中国现代医学杂志,2008,18(5):631-633.
作者姓名:郝继山  杨玉山
作者单位:1. 天津市人民医院,天津,300121
2. 天津市环湖医院,天津,300060
摘    要:目的探讨外周血中循环血管内皮细胞(circulating endothelial cells,CECs)与胶质瘤的关系。方法流式细胞法检测59例初诊胶质瘤患者外周血中的CECs的水平。结果治疗前后循环血管内皮细胞数量变化与胶质瘤患者的性别、年龄、病理类型、肿瘤负荷无关;治疗前后循环血管内皮细胞数量变化在不同疗效、肿瘤进展时间(time to progress,TTP)、1年生存率组有差异。结论提示循环血管内皮细胞是评价胶质瘤近期和远期疗效的指标。

关 键 词:胶质瘤  循环血管内皮细胞  血管生成  外周血  血管内皮  细胞数量  胶质瘤  关系  endothelial  cells  circulating  Relationship  指标  远期疗效  评价  差异  生存率  time  progress  肿瘤进展时间  肿瘤负荷  病理类型  年龄  性别
文章编号:1005-8982(2008)05-0631-03
修稿时间:2007年8月11日

Relationship between circulating endothelial cells(CECs) and glioma
HAO Ji-shan,YANG Yu-shan.Relationship between circulating endothelial cells(CECs) and glioma[J].China Journal of Modern Medicine,2008,18(5):631-633.
Authors:HAO Ji-shan  YANG Yu-shan
Institution:HAO Ji-shan1,YANG Yu-shan2 (1.People\'s Hospital of Tianjin City,Tianjin 300121,P.R.China,2.Tianjing Huanhu Hospital,Tianjin 300060,P.R.China)
Abstract:Objective] To investigate the relationship between circulating endothelial cells(CECs) and Glioma. Methods] CECs of 59 patients with glioma were isolated by using an antibody directed against CD146, then it were quantified by flow cytometry analysis. Results] No significant difference was found in amount of CECs before treatment or CECs amount between pre-and post-therapy in different sex, age, patho-type, tumor size. Significant difference was found in amount of CECs amount between pre-and post-therapy ...
Keywords:glioma  circulating endothelial cells  angiogenesis  
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