| 入肝血流阻断和全肝血流阻断对肝组织氧压影响 |
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| 引用本文： | 王成友,倪勇,何海萍.入肝血流阻断和全肝血流阻断对肝组织氧压影响[J].中华肝胆外科杂志,2002,8(11):678-679. |
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| 作者姓名： | 王成友 倪勇 何海萍 |
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| 作者单位： | 518035,深圳市,深圳市第二人民医院肝胆外科 |
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| 基金项目： | 广东省医药科技基金及深圳市科技局资助项目(A19985 5 0,2 0 0 0 0 40 31) |
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| 摘 要： | 目的 研究兔常温下入肝血流阻断（portal triad clamp,PTC)及全肝血流阻断（total hepatic vascular exclusion,THVE)对肝组织氧压（tissue oxygen pressure,Ptio2)的影响。方法 24只兔均分二组即PTC和THVE组。分别测定二组缺血前、缺血30min及再灌注30min后肝Ptio2值及血清丙氨酸氨基转氨酶（ALT）值变化。结果 PTC和THVE组均表现为肝Ptio2下降，但THVE较PTC组肝Ptio2值下降更显著（P＜0．01）、血清ALT值也明显升高（P＜0．05）。结论 PTC组较THVE组对肝缺血的耐受性增加。
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| 关 键 词： | 再灌流损伤 肝损伤 氧压 肝血流阻断 全肝血流阻断 |
| 修稿时间： | 2001年8月13日 |
Changes of hepatic tissue Ptio2 in ischemia-reperfusion injury induced by PTC and THVE |
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| WANG Chengyou,NI Yong,HE Haiping.Changes of hepatic tissue Ptio2 in ischemia-reperfusion injury induced by PTC and THVE[J].Chinese Journal of Hepatobiliary Surgery,2002,8(11):678-679. |
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| Authors: | WANG Chengyou NI Yong HE Haiping |
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| Institution: | WANG Chengyou,NI Yong,HE Haiping. Department of Hepatobiliary Surgery,the Second People's Hospital of Shenzhen City,Shenzhen 518035,P. R. China |
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| Abstract: | ObjectiveTo investigate changes of rabbit hepatic tissue Ptio 2 in ischemia-reperfusion injury induced by portal triad clamping (PTC) and total hepatic vascular exclusion (THVE). MethodsTwenty-four rabbits were divided into 2 groups: PTC group and THVE group. During liver ischemia and reperfusion, hepatic Ptio 2 and serum ALT were monitored. ResultsHepatic Ptio 2 decreased and serum ALT increased during hepatic ischemia. The value of Ptio 2 was markedly higher but that of serum ALT lower in PTC group than in THVE group (P<0.01 and 0.05). ConclusionsThe liver in PTC group can tolerate ischemia longer. |
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| Keywords: | Reperfusion injury Liver Injury Oxygen pressure |
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