ELISA versus PCR for diagnosis of chronic Chagas disease: systematic review and meta-analysis |
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| Authors: | Pedro EAA Brasil Liane De Castro Alejandro M Hasslocher-Moreno Luiz HC Sangenis José U Braga |
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| Affiliation: | 1.Instituto de Pesquisa Clínica Evandro Chagas - Funda??o Oswaldo Cruz,Rio de Janeiro/RJ,Brazil;2.Instituto de Medicina Social - Universidade do Estado do Rio de Janeiro,Brazil;3.Centro de Referência Professor Hélio Fraga - Escola Nacional de Saúde Pública - Funda??o Oswaldo Cruz,Brazil |
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| Abstract: | Background Most current guidelines recommend two serological tests to diagnose chronic Chagas disease. When serological tests are persistently inconclusive, some guidelines recommend molecular tests. The aim of this investigation was to review chronic Chagas disease diagnosis literature and to summarize results of ELISA and PCR performance. |
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