Local staging of prostate carcinoma with endorectal coil MRI: correlation with whole-mount radical prostatectomy specimens |
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| Authors: | C. Bartolozzi I. Menchi R. Lencioni S. Serni A. Lapini G. Barbanti A. Bozza A. Amorosi A. Manganelli M. Carini |
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| Affiliation: | (1) Department of Radiology, University of Pisa, Via Roma 67, I-56125 Pisa, Italy;(2) IPR Radiological Center, Viale della Repubblica 153, I-50047 Prato, Italy;(3) Department of Urology, University of Florence, Viale Morgagni 85, I-50134 Florence, Italy;(4) Department of Urology, University of Siena, Viale Bracci, I-53100 Siena, Italy;(5) Department of Pathology, University of Florence, Viale Morgagni 85, I-50134 Florence, Italy |
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| Abstract: | The purpose of this study was to investigate the accuracy of endorectal coil MRI in the local staging of prostate carcinoma. A total of 73 patients with biopsy-proven prostate carcinoma were examined at 0.5 T prior being submitted to radical prostatectomy. The gold standard was provided in all patients by findings at whole-mount sectioning of the surgical specimens. At pathology 28 patients had stage T2, 30 had stage T3a/b, and 15 had stage T3c lesions. Overall accuracy of endorectal coil MRI in defining local tumor stage was 82% (60 of 73 patients). Of 73 patients, 5 (7%) were underestimated and 8 (11%) overestimated. The sensitivity and the specificity of endorectal coil MRI in diagnosing capsular penetration were 95% and 82%, respectively. Seminal vesicle invasion was detected with 80% sensitivity and 93% specificity. Our data indicate that endorectal coil MRI is an accurate method for local staging of prostate cancer.Correspondence to: C. Bartolozzi |
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| Keywords: | Magnetic resonance Surface coils Prostate Neoplasms Seminal vesicle |
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