| 鼠纤维母细胞磷脂酰肌醇代谢池的研究 |
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| 引用本文： | 彭愈生,任丽君,马玉彦. 鼠纤维母细胞磷脂酰肌醇代谢池的研究[J]. 齐齐哈尔医学院学报, 1992, 0(3) |
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| 作者姓名： | 彭愈生 任丽君 马玉彦 |
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| 作者单位： | 哈尔滨医科大学肿瘤研究所，哈尔滨医科大学肿瘤研究所，哈尔滨医科大学肿瘤研究所 |
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| 摘 要： | 本文对鼠纤维母细胞的PI-P001进行了初步探讨。实验证明只有在激素存在的条件下,进行同位素预标记的细胞才能对肾上腺素进行应答,即肾上腺素可促进其〔~H3〕PI的分解。说明鼠纤维母细胞中具有对肾上腺素反应性不同(敏感及不敏感)的两种PI-P001。实验还证实Na_2SeO_3可阻碍细胞对肾上腺素的PI效应。
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| 关 键 词： | 鼠纤维母细胞 磷脂酰肌醇代谢池 磷脂酰肌醇效应 |
THE INITIAL STUDY OF PI-POOL IN FLBROBIAST |
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| Peng YuSheng et al. THE INITIAL STUDY OF PI-POOL IN FLBROBIAST[J]. Journal of Qiqihar Medical College, 1992, 0(3) |
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| Authors: | Peng YuSheng et al |
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| Abstract: | We report here the study of PI-pooL in fibroblast. We observed that epinephrine was able to stimulate turnover of prelabeled, radioactive PI. Only cells which had been preinCubated with [3H] in ositol in the presence of hormone were able to subsequently respond to the hormone by increased loss of radio-activity from PI. Thus we suggest the existence of tow pools of PI (hormone-sensitive, insensitive) in fibroblast. In addition, Na2SeO3 inhibited PI hydrolysis of fibroblast. |
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| Keywords: | Fibroblast Pl-Pool |
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