Lens intermediate filaments |
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| Authors: | Paul G FitzGerald |
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| Institution: | Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, CA 95616, USA |
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| Abstract: | The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed. |
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| Keywords: | lens Intermediate filaments beaded filaments vimentin filensin CP49 Phakinin Phakosin |
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