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2型糖尿病高血压患者血浆内源性分泌型晚期糖基化终末产物受体和氧化应激的关系
引用本文:沈兴平,邹森彪,吴豪杰,张岩. 2型糖尿病高血压患者血浆内源性分泌型晚期糖基化终末产物受体和氧化应激的关系[J]. 中华内分泌代谢杂志, 2009, 25(2). DOI: 10.3760/cma.j.issn.1000-6699.2009.02.014
作者姓名:沈兴平  邹森彪  吴豪杰  张岩
作者单位:厦门大学附属中山医院内分泌科,361004
摘    要:探讨2型糖尿病高血压患者血浆内源性分泌型晚期糖基化终末产物受体(esRAGE)与氧化应激的关系.结果 显示2型糖尿病患者esRAGE与体重指数(BMI,r=-0.33)、舒张压(r=-0.38)、氧化应激均显著相关(均P
关 键 词:糖尿病,2型  晚期糖基化终末产物受体  氧化应激

Relationship between plasma level of endogenous secretory receptor of advanced glycation end products and oxidative stress in diabetic patients with hypertension
SHEN Xing-ping,ZOU Sen-biao,WU Haovjie,ZHANG Yan. Relationship between plasma level of endogenous secretory receptor of advanced glycation end products and oxidative stress in diabetic patients with hypertension[J]. Chinese Journal of Endocrinology and Metabolism, 2009, 25(2). DOI: 10.3760/cma.j.issn.1000-6699.2009.02.014
Authors:SHEN Xing-ping  ZOU Sen-biao  WU Haovjie  ZHANG Yan
Abstract:The relationship between plasma level of endogenous secretory receptor of advanced glyeation end products(esRAGE)and oxidative stress in diabetic patients with hypertension was investigated.The results showed that there was significant negative correlation between esRAGE and body mass index(BMI,r=-0.33), diastolic blood pressure(DBP,r=-O.38)and oxidative stress(all P<0.05).The levels of plasma esRAGE decreased significantly in diabetic patients with hypertension.BMI,DBP and oxidative stress may participate in determinining the esRAGE level in diabetic patients complicated with hypertension.
Keywords:Diabetes mellitus,type 2  Advanced glycation end product receptor  Oxidative stress
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