抗生素“降阶梯疗法策略”在老年重症肺炎的应用

目的探讨老年重症肺炎抗生素治疗的疗效。方法将38例老年重症肺炎随机分为降阶梯疗法组20例,升阶梯疗法组18例两组,初期分别观察用药后的临床疗效、住院时间及费用。结果降阶梯疗法组总有效率达90.00%,明显高于升级组(55.55%),且可缩短肺部啰音消失时间、并发症的控制时间及总住院日期,降低病死率,避免耐药菌的产生,减少二重感染的发生率。结论抗生素“降阶梯疗法策略”治疗老年重症肺炎的总的投资效益比优于升阶梯组,值得在临床推广应用。

The Application of De-escalation Antibiotics Therapy to the Old Patients with Severe Pneumonia

Objective To study the effect of antibiotics therapy in the old patients with severe pneumonia.Methods All the 38 old patients with severe pneumonia were divided into two groups at random,which were respectively called treatment group(20 cases) treated with de-escalation antibiotics therapy and control group(18 cases) with escalation antibiotics therapy.The clinical effects and the length and the cost of hospitalization were analyzed.Results The effective rate(90.00%) of the treatment group with de-escalation antibiotics therapy is higher than that(55.55%) of the control group.The rale in the lungs and the complication vanished earlier in the treatment group,and its mortality,as well as the incidence rate of double infections,was lower.Conclusion De-escalation antibiotics therapy in elder patients with severe pneumonia is better than escalation antibiotics therapy,and worth spreading clinically.