手术治疗人乳头瘤病毒感染皮损

目的分析手术治疗人乳头瘤病毒感染所致的巨大或广泛性皮损的疗效。方法对有巨大或广泛性皮损的10例寻常疣、20例尖锐湿疣、8例疣状表皮发育不良难治性病例进行外科手术治疗。结果术后6个月,10例寻常疣患者中,有2例部分原位复发。20例尖锐湿疣患者,5例复发,复发率为25%。8例疣状表皮发育不良患者经手术将严重皮损去除,所有病例肢体功能均恢复正常,但并不能完全彻底根治,后经长期给予外用维A酸类等药物,病情得以控制,增生皮损均未超出原病变皮损,肢体功能无障碍。结论外科手术是治疗巨大或广泛性人乳头瘤病毒感染皮损可选择的手段。

Surgical treatment of skin lesions infected with human papilloma virus

Objective To report the surgical approach for the treatment of giant or extensive skin lesions due to the infection of human papilloma virus (HPV). Method Surgical treatment was performed for 10 patients with verruca vulgris, 20 with condyloma acuminatum, and 8 with epidermodyplasia verruciformis, whose giant or extensive lesions were poorly responsive to routine non-surgical therapy. Results Recurrence of lesions was found in 2 of 10 patients with verruca vulgris and 5 of 20 condyloma acuminatum in 6 months after operation, with a total recurrent rate of 25%. The extensive skin lesions were removed and the functions of affected limbs were recovered in patients with epidermodyplasia verruciformis after operation, however, the long-term topical retinoids was needed to control the recurrence of the lesions. Conclusion Surgical approach is effective for the treatment of the giant or extensive skin lesions due to HPV infection.