急性脑梗死后血管性认知障碍发病率的相关研究

目的探讨急性脑梗死后血管性认知障碍的发病率及影响因素。方法依据蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)将200例急性脑梗死住院患者分为有认知障碍组和无认知障碍组。统计急性脑梗死后血管性认知障碍的发生率,并分析不同性别、不同年龄、不同文化程度、多次(≥2次)脑梗死史与发病率之间的关系。结果急性脑梗死后血管性认知障碍的发生率为45.0%;其中,首次脑梗死后认知障碍的发生率为32.5%,多次脑梗死患者认知障碍的发生率为64.9%,差异有统计学意义(P0.05)。急性脑梗死后认知障碍的发生率随年龄的增加有上升趋势,差异有统计学意义(P0.05)。急性脑梗死后认知障碍的发生率随文化程度的提高有下降趋势,差异有统计学意义(P0.05)。不同性别间急性脑梗死后认知障碍的发生率差异无统计学意义(P0.05)。结论多次脑梗死患者较首次脑梗死患者血管性认知障碍的发生率高;急性脑梗死后认知障碍的发生率随年龄的增加而升高,随文化程度的提高而降低。

Study of the incidence of vascular cognitive impairment in acute cerebral infarction patients

Objective To investigate the incidence and the influence factors of vascular cognitive impairment(VCI) in acute cerebral infarction patients.Methods Two hundred cases with acute cerebral infarction were divided into VCI group and non-VCI group based on Montreal cognitive assessment(MoCA).Then the incidence of VCI was calculated and the relations between the gender,age,education level,the history and frequency of cerebral infarction and VCI were analyzed.Results The incidence of VCI in acute cerebral infarction patients was 45.0 ％,and initial-infarction group had lower incidence of 32.5 ％ than multi-infarction group of 64.9 ％,with a statistically significant difference(P＜0.05).There was significant difference that with the age increasing,the incidence of VCI trended to be escalating(P＜0.05).On the contrary,the higher the education levels,the lower incidence occurred(P＜0.05).No significant difference was found regarding the gender(P＞0.05).Conclusion Patients with multi-cerebral infarction have higher incidence of vascular cognitive impairment;and the incidence may have positive correlation with the age and have negative correlation with education level.