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中药成分抗结肠癌的作用机制研究进展
引用本文:张季林,陈丽玲,刘利艳. 中药成分抗结肠癌的作用机制研究进展[J]. 江西中医学院学报, 2011, 23(5): 96-98
作者姓名:张季林  陈丽玲  刘利艳
作者单位:1. 江西省人民医院中医科 南昌 330006
2. 江西中医学院实验动物科技中心 南昌 330006
3. 江西省第二人民医院药剂科 南昌 330029
摘    要:某些中药及天然药物来源的成分具有肯定的抗结肠癌作用,它们可以通过调控基因表达抑制细胞增殖及诱导细胞凋亡、作用于肿瘤细胞的细胞周期、诱导细胞凋亡并阻断细胞周期等途径发挥抗结肠癌作用,其结构各异,为探索抗肿瘤新药研发提供了依据,并为药物结构的修饰奠定了基石。

关 键 词:中药成分  抗结肠癌  作用机制

Progress on Anti-Colon Carcinoma Mechanism of Active Ingredients in Traditional Chinese Medicine
ZHANG Ji-lin,CHEN Li-lin,LIU Li-yan. Progress on Anti-Colon Carcinoma Mechanism of Active Ingredients in Traditional Chinese Medicine[J]. Journal of Jiangxi College of Traditional Chinese Medicine, 2011, 23(5): 96-98
Authors:ZHANG Ji-lin  CHEN Li-lin  LIU Li-yan
Affiliation:ZHANG Ji-lin1,CHEN Li-ling2,LIU Li-yan3 1.Department of traditional Chinese medicine,Jiangxi people's Hospital.Nanchang,330006,2.Laboratory Animal Science and Technology Center,Jiangxi University of Traditional Chinese Medicine.Nanchang,3.Department of pharmacy,Second people's Hospital of Jiangxi Province.Nanchang,330029.
Abstract:There are some active ingredients in traditional Chinese medicine and natural medicine with a certain role in anti-Colon Carcinoma through a variety of different mode of action in tumor cells cycle,including regulation of gene expression,inhibition of cell proliferation,induction of apoptosis,blocking cell cycle and so on.In addition,these effective ingredients have different structures.These findings provided basis for the development of antineoplastic drug and laid the foundation for the drug structure mo...
Keywords:Traditional Chinese Medicine Ingredients  Anti-Colon Carcinoma  Mechanism of Action  
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