短期高强度军事作业对个体疲劳感及内分泌功能的影响

目的 研究短期高强度军事作业诱发疲劳的特点和神经-内分泌改变规律.方法 2010年解放军总医院在某部为期7d高强度军事演习作业前后,分析240名官兵疲劳发生状况及垂体-肾上腺（包括血浆促肾上腺皮质激素、皮质激素、24 h尿游离皮质醇）、垂体-性腺（黄体生成素、睾酮、雌二醇）、垂体-甲状腺（血清TSH、TT4、TT3、FT4和FT3）轴激素水平改变.结果 高强度军事作业后,官兵作业疲劳症状自评量表中不快感分量表得分增加（7.53±2.64 ys 8.02±3.06,P＜0.05）;皮质醇由（336.97±105.23） nmol/L降至（283.94±84.61） nmol/L（P＜0.001）,24h尿游离皮质醇由（426.39±162.35） nmol/24 h降至（371.76±155.51） nmol/24 h（P＜0.001）、TT3由（2.13±0.30） nmol/L升至（2.72±2.26） nmol/L（P＜0.05）,FT4由（13.45±1.45） pmol/L升至（15.92±1.95） pmol/L（P＜0.001）,FT3由（5.23±0.42） pmol/L升至（5.61±0.58） pmol/L（P＜0.001）,睾酮水平由（23.51±6.49） nmol/L降至（18.89±5.89） nmol/L（P＜0.001）.结论 短期高强度军事作业可增加官兵的疲劳状况,影响神经-内分泌系统.

Effects of high intensive short-term military operations on fatigue and neuroendocrine

Objective To investigate the features of the fatigue caused by high intensive short-term military operations and regulation changes of the nerves- endocrine- system. Methods Clinical data about 240 officers who took high intensive short-term military operations for seven days, including the pituitary - adrenal hormone （ACTH, Cortisol, UFC）, pituitary - gonadal hormone （LH, FSH, T, E2）, pituitary - thyroid hormone （TSH, TT3, T3, TT4, T4）, were detected and analyzed using Fatigue Assessment Scale. Results After the 7-day military operations, the subjects＇ feeling of unpleasurement in faigue scales significantly increased （1.47 ±0.44 vs 1.61 ± 0.52, P 〈 0.05）, while the adrenal cortex function reduced （Cortisol from 336.97 ±105.23 nmol/L to 283.94 ± 84.61 nmol/L, UFC from 426.39±162.35 nmol/24 h to 371.76± 155.51 nmol/24 h）, testosterone level reduced （T from 23.51 ± 6.49 nmol/L to 18.89±5.89 nmol/L）, and thyroid function increased （TT3 from 2.13 ±0.30 nmol/L to 2.72± 226 nmol/L, FF4 from 13.45 ± 1.45 pmol/L to 15.92 ± 1.95 pmol/L, FT3 from 5.23 ±0.42 pmol/L to 5.61 ± 0.58 pmol/L）. Conclusion High intensive short-term operations can increase the feeling of fatigue and then seriously affect the psychology Neuro - endocrine system of the officers.