Abstract: | Objective To evaluate the relevant factors of regression phenomenon of laser in situ keratomileusis (LASIK) for treatment of myopia.MethodsWe studied 408 eyes of 250 myopic patients who received LASIK. Patients were divided into 2 groups according to preoperative diopters (-6.00D~10.00D, 194 eyes;-10.10D~-15.00D, 214 eyes). Mean period of follow up were 12 months and the results were statistically analyzed.Results12 months after surgery, in the first group (-6.00D~-10.00D) the regression equal to or beyond -1.0D were 21 eyes (10.8%), range from1.0D to3.0D. The average regression was 1.33D. In the second group (-10.10D~-15.00D) regression equal to or beyond -1.0D were 78 eyes (36.5%), range from 1.0D to -5.50D. The average regression was 1.99D.ConclusionThe results indicate that excimer LASIK can be used to treat myopia between -6.00D~-15.00D effectively with minimal regression within 12 months. Preoperative thin corneas with intraoperative small ablation zone could induce regression. Some modification of the surgical algorithms and laser nomogram will help to improve predictability and reduce regression. |