整形门诊手术前后抗生素应用对比观察

本文总结了１５４６例整形门诊手术病例，通过对术前、术后使用抗生素的对比观察，说明在手术室条件不变及术者相对固定的情况下，术前预防性使用抗生素优于术后使用抗生素。所有病例分术前用药组和术后用药组，按手术类型、手术部位、急诊与否、有否植入体等分项对比，并就对比项目列表作统计学分析。结果表明术前使用抗生素感染率为０％，术后组为２．９１％，经统计学分析Ｐ＜０．００１。结论：①通过对比观察，表明术前用药可有效地发挥抗生素作用，降低感染率，优于术后用药；②有植入体或涉及软骨组织的手术宜术前使用抗生素，急诊手术或血供较差部位的手术应术前使用抗生素；③选择的药物应抗菌谱广，吸收迅速，低价，使用方便。术前用药强调剂量要足量；④术前抗生素应在术前２小时内给药。

Observation on pre-operative versus post-operative antibiotics prophylaxis in outpatients underwent plastic surgery

To observe the advantages of pre-operative antibiotic prophylaxis as compared with its post-operative administration, 1546 cases were devided into two groups: one pre-operative antibiotic prophylaxis and one post-operative. The important items compared were listed and statistically analysed. Results: The infection rate of the pre-operative antibiotic prophylaxis group was 0%while that of the other one was 2.91%( P <0.001). Conclusions: It was proved that pre-operative antibiotic prophylaxis was more effective than its post-operative application in reducing infection rate. It improved that pre-operative antibiotic had great advantage, especially in such operations: emergency operation. operations involving cartilage and in the area of insufficient blood supply. Broad spectrum antibiotics with rapid and complete absorption and low cost were the first choice. It also required that the blood concentration of it reached its peak in 60 minutes. Antibiotics should be given within 2 hours before operation.