办公大楼内环境与黏膜刺激体征关系的多因素分析

目的 本文旨在分析上海冬季封闭式建筑物室内环境因素与人群眼、鼻、咽喉黏膜刺激体征阳性率之间是否存在剂量－反应关系。方法 1997年1998年冬季，选择竣工10年以内的27幢办公大楼，测试春现场环境指标，并对其内在832名工作人员进行眼、鼻、咽喉黏膜的体检。以环境指标及性别与否有黏膜刺激体征建立Logistic回归模型。结果 环境因素中与眼结膜刺激体征阳性率有显著相关的有：空气总颗粒物、人均面积、相对湿度和亮度；与五官黏膜刺激体征阳性率有显著相关的有：温度和相对湿度。结论 空气总颗粒物对眼结膜刺激影响较大，温度和相对湿度偏低，但偏回归系数值较小。人群黏膜系统对总体情况的敏感性强于某单个因素。

Multi-factor Analysis on Relationgship between Mucosa Irritation Signs and Office Building Environment

Objective] To analysis the dose response relationship between eye,nose and throat irritation and indoor environment in the sealed buildings in winter in Shanghai. [Methods] 27 office buildings constructed after 1986 were monitored and 832 office workers were undergone medical examination. Set up logistic regression model between environment factors, sex and mucosa irritation signs. [Results] Dust,area,relative humidity and brightness were correlated to the rates of eye irritation signs significantly;while temperature and relative humidity were correlated to the rates of nose and throat irritation signs. [Conclusion] Dust can mainly affect the rates of eye irritation,temperature and relative humidity were somewhat lower,but the value of b was small. Mucosa system is more sensitive to general situation than to single factor.