| 组织工程全层皮肤修复糖尿病性皮肤溃疡创面的临床研究 |
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| 引用本文： | 肖厚安,金岩,吴周虎,聂鑫,张勇杰,鲁美茹,刘亚玲.组织工程全层皮肤修复糖尿病性皮肤溃疡创面的临床研究[J].中华损伤与修复杂志,2008,3(2):9-11. |
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| 作者姓名： | 肖厚安 金岩 吴周虎 聂鑫 张勇杰 鲁美茹 刘亚玲 |
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| 作者单位： | [1]西安市铁路中心医院烧伤整形科,710054 [2]第四军医大学组织工程中心,西安710032 [3]第四军医大学西京医院烧伤科,西安710032 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 目的探讨利用组织工程全层皮肤（ActivSkin）修复糖尿病性皮肤溃疡创面的临床应用方法。方法对皮肤溃疡患者采用控制血糖、增如营养、防治感染等措施，ActivSkin直接覆盖于创面，创面分3层包扎，常规换药，分别于术后观察组织工程皮肤的有效性及安全性。结果患者术后病情平稳，可见ActivSkin在创面存活，创面边缘可见白色新生组织形成，随时间延长创面逐渐缩小，平均28d后达到临床愈合。结论利用ActivSkin修复糖尿病性皮肤溃疡创面可促进创面早期修复、缩短病程和降低由此产生的致残率；为ActivSkin的临床应用提供了切实可行的方法。
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| 关 键 词： | 组织工程 糖尿病溃疡 创面修复 |
The clinic application of tissue engineered active skin on the diabetic ulcer |
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| XIAO Houan,JIN Yan,WU Zhouhu,NIE Xin,ZHANG Yongjie,LU Meiru,LIU Yaling.The clinic application of tissue engineered active skin on the diabetic ulcer[J].Chinese Journal of Injury Repair and Wound Healing,2008,3(2):9-11. |
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| Authors: | XIAO Houan JIN Yan WU Zhouhu NIE Xin ZHANG Yongjie LU Meiru LIU Yaling |
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| Institution: | XIAO Houan,JIN Yan,WU Zhouhu,NIE Xin,ZHANG Yongjie,LU Meiru,LIU Yaling.Department of Burns , Plastic Surgery,Xi\'an Railway Central Hospital,Xi\'an 710054,China |
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| Abstract: | Objective To study a good clinic application methods of tissue engineered active skin(ActivSkin) on the greatscale diabetic ulcer.Methods patient with skin ulcer was treated with following measures:controlling blood sugar,enhancing nutrition and preventing infection during preoperation,after surgical debridement,TEskin were applied directly on the wound and threelayer wound dressing to deal with skin ulcer.Results illness condition was stable.The graft continuous persists in the wound and to stimulate wound... |
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| Keywords: | Tissue engineer Diabetic ulcer Wound repair |
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