Bone marrow blood supply in gadolinium-enhanced magnetic resonance imaging |
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Authors: | A Saifuddin K Bann J P Ridgway W P Butt |
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Institution: | (1) MRI Unit, St. James's University Hospital, Leeds, UK;(2) Chancellor's Wing X-Ray, St James's University Hospital, LS9 7TF Leeds, UK |
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Abstract: | A retrospective study was performed to determine whether bone blood supply can be assessed on gadolinium-enhanced magnetic resonance imaging. Lumbar spine magnetic resonance imaging (MRI) examinations of 49 patients attending for post-laminectomy examination were reviewed (30 male, 19 female, mean age 46.4 years, age range 23–84 years). Each study included sagittal T1-weighted spin echo sequences before and after gadolinium administration. Regions of interest were drawn within the L3 vertebral body from a parasagittal slice from each sequence. Signal intensity (SI) values were ascertained and the percentage increase in SI was calculated. For each patient, changes in receiver gain for pre and post-gadolinium images were corrected by an image scaling factor. In all cases, a measurable increase in SI was found (mean 15.3%, range 4.4–55.7) due to bone vascularity. The results give no indication of the quantity or timing of blood supply but provide a basis for further work. |
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Keywords: | Bone marrow Blood supply Magnetic resonance imaging Enhancement Lumbar spine Gadopentetate dimeglumine |
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