Substance P-, somatostatin-, vasoactive intestinal peptide- and cholecystokinin-like levels in the spinal cord of polyarthritic rats |
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Authors: | S. Chery-Croze L. Kocher C. Bernard J. A. Chayvialle |
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Affiliation: | 1. Department of Chemical and Biological Engineering, University of Alabama, Tuscaloosa 35487, United States;2. Center of Materials for Information Technology, University of Alabama, Tuscaloosa 35487, United States |
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Abstract: | Substance P-, somatostatin-, vasoactive intestinal polypeptide- and cholecystokinin-like levels were measured in lumbar dorsal and ventral cord of polyarthritic rats and compared with those obtained in vehicle-treated rats taken as controls. Polyarthritis decreased substance P concentration in lumbar ventral cord and increased cholecystokinin level in lumbar dorsal cord, while the other two peptides did not show any change. The results are discussed in relation to immunohistochemical data found in the literature. |
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Keywords: | substance P somatostatin vasoactive intestinal peptide (VIP) cholecystokinin polyarthritic rat spinal cord peptide |
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