噻氯匹定联合曲美他嗪治疗不稳定型心绞痛的疗效评价

目的评价噻氯匹定联合曲蔓他嗪治疗不稳定型心绞痛的疗效。方法将我院96例符合标准的不稳定型心绞痛患者随机分为对照组（48例）和治疗组（48例）。对照组患者给予基础治疗（硝酸酯类，β-受体阻滞剂，抗凝剂及阿司匹林等），治疗组在此基础上加用噻氯匹定＋曲美他嗪，疗程均为4周，治疗前、后检查心电图。记录心绞痛发作次数厦每次心绞痛发作的平均时间。结果两组患者临床疗效间差异有显著性意义（P〈0．01）。治疗组患者治疗前、后心绞痛发作次数、持续时间及对照组患者治疗前、后心绞痛发作次数间差异均有显著性意义（P〈0．05）。两组患者治疗后心绞痛发作次数、持续时间差异亦均有显著性意义（P〈0．05）。结论噻氯匹定联合曲美他嗪治疗不稳定型心绞痛疗效确切，值得临床推广使用。

Clinical Evaluation of Ticlopidine Combined with Trimedazidine on Improving Unstable Angina Pectoris (UAP)

Objective To study the effect of ticlopidine combined with trimedazidine on improving UAP in patatients.Methods Ninty-six patients with UAP were divided into two groups by randomly:the controlled group (n=48) and the test group(n=48),after 4 weeks therapy,Evalute the clinical effect and change of the electrocardiogram and the frequency and the lasting time of angina.Results Following therapy for 4 weeks,the efficiency of the test group and controlled group were 89.5% and 68.7%,the change of the electrocardiogram were 76% and 54.2%.the frequency and the lasting time of angina were improve significantly in the test group (P<0.01).Conclusion Ticlopidine combined with trimedazidine can improve the UAP in patients,and it is valuable to be spread broadly in clinic.