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肺癌脑转移治疗研究进展
引用本文:孙君昭,程岗,张剑宁. 肺癌脑转移治疗研究进展[J]. 肿瘤防治研究, 2022, 49(6): 522-527. DOI: 10.3971/j.issn.1000-8578.2022.21.1456
作者姓名:孙君昭  程岗  张剑宁
作者单位:100853 北京,中国人民解放军总医院神经外科医学部
摘    要:肺癌是中国发病率和死亡率最高的恶性肿瘤,而且在疾病发展过程中易发生脑转移,严重影响患者的生存质量以及生存期。肺癌脑转移的治疗方法包括外科手术、化疗、全脑放射治疗、立体定向放射外科治疗、分子靶向治疗、免疫治疗以及抗血管生成治疗等。对于不同患者如何选择合理且有效的治疗方案是目前研究的热点之一。本文将对肺癌脑转移治疗相关研究进展进行综述,以期为肺癌脑转移患者选择更合理的临床治疗方案提供参考。

关 键 词:全脑放疗  肺癌  靶向治疗  脑转移  免疫治疗  立体定向放射外科  抗血管生成治疗
收稿时间:2021-12-14

Advances in Treatment of Brain Metastasis from Lung Cancer
SUN Junzhao,CHENG Gang,ZHANG Jianning. Advances in Treatment of Brain Metastasis from Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2022, 49(6): 522-527. DOI: 10.3971/j.issn.1000-8578.2022.21.1456
Authors:SUN Junzhao  CHENG Gang  ZHANG Jianning
Affiliation:Department of Neurosurgery, Chinese PLA General Hospital, Beijing 100853, China
Abstract:Lung cancer is the malignant tumor with the highest incidence and mortality in China, and is prone to brain metastasis in the process of disease development, which seriously affects the quality of life and survival of patients. The treatment methods for brain metastasis of lung cancer include surgery, chemotherapy, whole brain radiotherapy, stereotactic radiosurgery, molecular targeted therapy, immunotherapy, antiangiogenesis therapy, etc. It’s one of the research hotspots to choose reasonable and effective treatment schemes for different patients. This paper reviews the research progress in the treatment of brain metastasis from lung cancer, to provide reference for selecting more reasonable clinical treatment for the patients.
Keywords:Lung cancer  Brain metastasis  Whole brain radiotherapy  Stereotactic radiosurgery  Targeted therapy  Immunotherapy  Antiangiogenesis therapy  
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