原发性肝细胞癌局部介入治疗新进展

原发性肝细胞癌是全球第6大常见恶性肿瘤，肿瘤相关性死亡中排名第三。我国肝癌发病率和病死率在男性和女性中均位列前五，且呈逐年上升趋势，而就诊时可手术切除的患者不到30%。随着医学技术的不断发展，介入治疗已在肝癌治疗中发挥着关键性作用。本文将重点对经动脉化疗栓塞、经动脉放射栓塞、经皮射频消融、微波消融等介入治疗方式，以及介入治疗与分子靶向、免疫联合治疗方面的最新进展作一综述。

Progress in Locoregional Interventional Therapy of Primary Hepatocellular Carcinoma

Primary hepatocellular carcinoma (HCC) is the sixth most common malignant tumor in the world, and ranks third in tumor-related deaths. The incidence and mortality of HCC in China are among the top five in both men and women, and are increasing year by year, while less than 30% of patients can be surgically resected. With the continuous development of medical technology, interventional therapy has played a key role in the treatment of HCC. This article reviews the latest progress of interventional therapy such as transarterial chemoembolization, transarterial radioembolization, radiofrequency ablation and microwave ablation, as well as interventional therapy combined with molecular targeted therapy and immunotherapy.