国内外癌因性疲乏的研究现状、热点演化与整合展望—基于文献计量学的可视化图谱分析

目的 对癌因性疲乏（CRF）国内外研究文献进行文献计量学分析，梳理国内外研究进展，呈现研究现状、分析热点演化趋势。方法 以癌因性疲乏为主题，以中国知识资源总库（CNKI）和 Web ofScience（WOS）核心数据库收录的有关癌因性疲乏论文为研究对象，采用VOSviewer和CiteSpace软件为研究工具，对国内外研究现状、热点演化进行可视化图谱分析。结果 （1）研究现状：①文献情况：最终纳入3646篇文献（英文1959篇，中文1687篇），中外发文量呈整体上升态势，国外基金论文占比高；②国内集中于护理与康复, 国外更广泛、多元、融合；③国内以小团体合作为主，国外跨学科、跨团队合作较多，形成了多个核心团队及研究机构群；④国内注重临床应用研究，善于借鉴国外和总结自身经验，国外更重视基础研究，治疗更系统化、规范化；⑤诊疗评估工具多样，以国外量表为主。（2）热点演化：“生活质量”一直是中外共同关注主题。国内注重临床研究，治疗上强调“审因论治”和“辨证论治”；国外重视基础研究与方法学研究，提倡运动等非药物干预；近年来补充替代医学成为国际研究热点，国内提高了对机制与方法学研究的重视，拓展了中医特色疗法在CRF中的应用。结论 中西医结合、多学科参与是CRF未来的诊疗模式，建立整合医学下中医特色非药物疗法为核心的CRF评估管理模式是未来的努力方向。

Current Status,Hot Spot Discovery and Integration Prospect of Cancer-related Fatigue Research at Home and Abroad Based on Bibliometric Visualization Map Analysis

Objective To review the research progress, present the research status and analyze the evolution trend of hot spots through the bibliometric analysis of the research literature of cancer-related fatigue(CRF) at home and abroad. Methods We took CRF as the theme and the papers on CRF included in CNKI and WOS core database as the research object, and used VOSviewer and CiteSpace software as research tools, to make a visual atlas analysis on the research status and hot spot evolution at home and abroad. Results (1)Research status:①Literature: 3 646 papers (1 959 in English and 1 687 in Chinese) were finally included. The number of papers published at home and abroad showed an overall upward trend, and the proportion of foreign fund papers was high; ②domestic papers focused on nursing and rehabilitation. The research area of foreign papers was more extensive, diverse and integrated; ③Domestic cooperation was mainly small group cooperation, while foreign cooperation was more interdisciplinary and cross-team cooperation, forming a number of core teams and research institutions; ④ Domestic scholars paid attention to clinical application research and were good at learning from foreign countries and summarizing own experience. Foreign scholars paid more attention to basic research and the treatment was more systematic and standardized; ⑤There were a variety of diagnostic and therapeutic evaluation tools, mainly foreign scales. (2) Hot spot evolution: "quality of life" had always been a common topic of concern at home and abroad. Domestic scholars focused on clinical research and emphasized "treatment based on examination of causes" and "treatment based on syndrome differentiation". Foreign scholars attached importance to basic research and methodological research, and advocated non-drug intervention such as sports. In recent years, complementary and alternative medicine had become a hot topic in the international research. Domestic scholars had paid more attention to the research of mechanism and methodology, and expanded the application of TCM characteristic therapy in CRF. Conclusion Integrated traditional Chinese and Western medicine and multi-disciplinary participation are the future diagnosis and treatment mode of CRF. It’s the direction of future efforts to establish CRF evaluation and management mode with TCM characteristic non-drug therapy as the core under integrated medicine.