脑垂体后叶素联合硝酸甘油治疗肺结核咯血临床观察

目的观察脑垂体后叶素联合硝酸甘油治疗肺结核咯血的疗效。方法44例患者随机分为两组:对照组(26例)予脑垂体后叶素及常规内科综合用药。治疗组(18例)在对照组基础上联用硝酸甘油(5mg/d)静脉滴注,疗程5~7天。结果治疗组和对照组止血率分别为83.3%和80.7%,治疗组略高于对照组,但无统计学差异(P>0.05)。治疗组不良反应发生率为10.1%,而对照组为42.4%,两组间有显著性差异(P<0.01)。结论脑垂体后叶素联合硝酸甘油能改善止血率,且不良反应大大降低,是治疗肺结核咯血的有效联合。

Clinical Observation on Pituitrin Combinded with Nitroglycerin Treating Hemoptysis Caused by Pulmonary Tuberculosis

Objective To observe the efficacy of pituitrin and nitroglycerin on hemoptysis caused by pulmonary tuberculosis.Method 44 cases were randomly divided into test group and control group.The control group(26 cases) was treated with pituitrin and other common medicines,while the test group(18 cases) was also treated with the same drugs but added nitroglycerin(5mg/d,intravenous drip for 5~7 days).Results The hemostatic rate was 83.3% and 80.7% respectively in test group and control group.It was slightly higher in test group than that in control group,but there was no significant difference(P>0.05).The side effect rate in test group was 10.1%,in control group it was 42.4%.The difference between two groups was signficant(P<0.01).Conclusions Pituitrin and nitroglycerin could improve the hemostatic rate and decrease side effects.They are effective on hemoptysis caused by pulmonary tuberculosis.