| 雷公藤多甙治疗原发性系膜增殖性肾炎的疗效观察 |
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| 引用本文： | 梁兰青,列才华,刘阳,冯维.雷公藤多甙治疗原发性系膜增殖性肾炎的疗效观察[J].西北国防医学杂志,2001,22(1):37-39. |
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| 作者姓名： | 梁兰青 列才华 刘阳 冯维 |
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| 作者单位： | 兰州军区乌鲁木齐总医院肾内科, |
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| 摘 要： | 目的：观察雷公藤多甙治疗原发性系膜增殖肾炎的疗效。方法：86例经肾活检确诊为系膜增殖性肾炎患者MsPGN49例、IgAN30例、IgMN7例，服用雷公藤多甙20－40mg,3.d^-1，4－8周。结果：治疗4周内45例（52．33％）病人获完全缓解，15例（17．44％）改善，治疗8例内总有效率87．21％，双倍剂量雷公藤多且与常规剂量组4周总有效率相比较，有极显著性差异（P＜0．01）。结论：雷公藤多甙对临床表现为肾病综合征、肾炎综合征，组织学病为轻－中度系膜增殖的MsPGN、IgAN具有良好的疗效。
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| 关 键 词： | 原发性系膜增殖肾炎性 雷公藤多甙 药物治疗 |
| 文章编号： | 1007-8622(2001)01-0037-03 |
| 修稿时间： | 2000年6月20日 |
Clinical effect of
tripterygium wilfordii in the treatment of prim ary mesagial proliferative
glomerulonephritis |
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| LIANG Lan-qing,LIE Cai-hua,LIU Yang,et al..Clinical effect of
tripterygium wilfordii in the treatment of prim ary mesagial proliferative
glomerulonephritis[J].Medical Journal of National Defending Forces in Northwest China,2001,22(1):37-39. |
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| Authors: | LIANG Lan-qing LIE Cai-hua LIU Yang |
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| Institution: | LIANG Lan-qing,LIE Cai-hua,LIU Yang,et al . |
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| Abstract: | Objective:To evaluate the clinical effect of tripterygium wilfordii(TW) on primary mesagial proliferative glomerulonephrit is.Methods:20～40 mg TW was given to 86 nephritis pa tients 3 times a day for 4－8 weeks,of whom included 49 mesagial proliferativeg lomerulonephritis (MsPGN)，30 IgA nephropathy(IgAN) and 7 IgM nephropathy(IgMN). Results:Complete remission was observed in 45 patien ts(52.33％) within 4 weeks and 50 patients within 8 weeks.Higher remission rate was observed in those patients treated with double dosage of TW(40 mg×3*d－1 ).Conclusion:TW shows as an effective clinical tre atment on MsPGN and IgAN. |
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| Keywords: | Nephritis Mesagial proliferative glomerulonephritis Tripterygium wilfordii |
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