Kétamine et dépression : vers de nouvelles perspectives thérapeutiques en soins de support ? |
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| Authors: | A Lemaire M Plançon M Bubrovszky |
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| Institution: | 1. Centre Hospitalier de Valenciennes, avenue Desandrouin, CS 50479, F-59322, Valenciennes cedex, France
2. Service de psychiatrie adulte, h?pital Fontan, CHRU de Lille, rue A.-Verhaeghe, F-59037, Lille cedex, France
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| Abstract: | Ketamine, a molecule mainly used as an analgesic in supportive oncology in particular in palliative care, turns out to be an excellent fast-acting antidepressant. By acting as an NMDA receptor antagonist, its mechanism of action is complementary to classical and long-acting antidepressants like selective serotonin reuptake inhibitors. These properties offer new perspectives in fast-controlling depression within the development of early palliative care in oncology. |
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