复方紫柄冬青软膏对烧烫伤细菌感染的体外抗菌活性研究1

目的：评价复方紫柄冬青软膏对临床常见菌种的抗菌活性。方法：采用中药抑菌实验方法，测定复方紫柄冬青软膏对3种实验菌（金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌）的体外抗菌活性。结果：经体外抗菌实验，其结果显示复方紫柄冬青软膏中含生药125（高浓度），62．50（中浓度）和15．62mg／mL（低浓度）的样品溶液，其高浓度对3种实验菌株均有抑制作用，中浓度对大肠埃希菌和铜绿假单胞菌有抑制作用，而低浓度仅对大肠埃希氏菌有抑制作用。结论：复方紫柄冬青软膏对金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌均有不同程度的抑菌活性。

Studies on Antibiotic Activity in Vitro of Compound Zibingdongqing Ointment in Bacteria Infection of Burn

Objective ： To evaluate the antibacterial effect of compound Zibingdongqing ointment in vitro. Meth- ods： Agar dilution method was used in an experimental study to determine the antibacterial effect of compound Zibing- dongqing ointment in vitro on three experiemental fungi （Staphylococcus aureus, Escherichia coli, Pseudomonas aerugi- nosa）. Results： 125 mg/mL of the drug had the antibacterial effect on the following three experiemental fungi; 62.5 mg/ mL of the drug had the antibacterial effect on Escherichia coli and Pseudomonas aureginosa; 15.62 mg/mL of the drug had the antibacterial effect on Escherichia coll. Conclusion： Compound Zibingdongqing ointment had varying degrees of the antibacterial effect on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa in vitro.