| 乙型肝炎病毒感染对妊娠期肝内胆汁淤积症妊娠结局影响研究 |
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| 引用本文： | 张盛燕,金丽桂,陈青娇. 乙型肝炎病毒感染对妊娠期肝内胆汁淤积症妊娠结局影响研究[J]. 中华医院感染学杂志, 2011, 21(22): 4725-4726 |
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| 作者姓名： | 张盛燕 金丽桂 陈青娇 |
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| 作者单位： | 1. 瑞安市妇幼保健院妇产科,浙江瑞安,325200
2. 瑞安市人民医院产科,浙江瑞安,325200 |
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| 基金项目： | 瑞安市科技局项目(201002086) |
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| 摘 要： | 目的探讨乙型肝炎病毒感染,对妊娠期肝内胆汁淤积症(ICP)妊娠结局的影响。方法对2009年8月-2010年11月收治的妊娠期肝内胆汁淤积症,合并乙型肝炎病毒感染的病例进行了回顾性分析,ICP合并HBV感染的孕妇48例作为研究组,102例无乙型肝炎病毒感染的ICP孕妇作为对照组,对2组孕妇妊娠期肝内胆汁淤积症的发生率、临床表现以及妊娠结局进行比较分析。结果与对照组相比,研究组孕妇妊娠期肝内胆汁淤积症发病率明显提高,达到3.9%,妊娠期肝内胆汁淤积症的发病时间明显提前,且分娩时间明显提前,早产率、剖宫产率以及产后出血的比率均明显提高,分别可达到64.6%、87.5%和31.3%,差异均有统计学意义(均P<0.05)。结论对于乙型肝炎病毒感染合并妊娠期肝内胆汁淤积症的孕妇,在采取相应治疗阻滞乙型肝炎母婴传播外,对孕妇进行密切的监测,以防止早产的发生,同时还要采取相应的措施预防产后出血,以确保母婴的健康。
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| 关 键 词： | 妊娠期肝内胆汁淤积症 乙型肝炎病毒 妊娠结局 |
Influence of hepatitis B virus infection on pregnancy outcomes of intrahepatic cholestasis of pregnancy |
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| ZHANG Sheng-yan,JIN Li-gui,CHEN Qing-jiao. Influence of hepatitis B virus infection on pregnancy outcomes of intrahepatic cholestasis of pregnancy[J]. Chinese Journal of Nosocomiology, 2011, 21(22): 4725-4726 |
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| Authors: | ZHANG Sheng-yan JIN Li-gui CHEN Qing-jiao |
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| Affiliation: | ZHANG Sheng-yan*,JIN Li-gui,CHEN Qing-jiao(*Maternal and Child Healthy Hospital of Ruian,Ruian,Zhejiang 325200,China) |
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| Abstract: | OBJECTIVE To probe into the influence of intrahepatic cholestasis on pregnancy outcomes inpatients with hepatitis B virus infection. METHODS Intrahepatic cholestasis with hepatitis B virus infections treated from Aug 2009 to Nov 2010 during pregnancy were retrospectively analyzed,ICP combined 48 cases of HBV infection in pregnant women as the study group,102 patients without B ICP hepatitis virus infection of pregnant women as a control group,two groups of pregnant women with intrahepatic cholestasis of pre... |
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| Keywords: | Intrahepatic cholestasis of pregnancy Hepatitis B virus Pregnancy outcomes |
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