| 莫西沙星治疗恶性肿瘤合并医院获得性肺炎的疗效观察 |
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| 引用本文： | 王伟华,郑逸华,周爱新,林雪梅,毛娟华,李振华. 莫西沙星治疗恶性肿瘤合并医院获得性肺炎的疗效观察[J]. 中华医院感染学杂志, 2011, 21(22): 4794-4796 |
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| 作者姓名： | 王伟华 郑逸华 周爱新 林雪梅 毛娟华 李振华 |
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| 作者单位： | 江山市人民医院呼吸内科,浙江江山,324100 |
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| 基金项目： | 浙江省医学会临床科研基金项目(2008CYC56) |
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| 摘 要： | 目的观察莫西沙星治疗恶性肿瘤合并医院获得性肺炎(HAP)的临床效果和安全性。方法 102例恶性肿瘤合并HAP病例,随机分为治疗组52例、对照组50例;治疗组应用莫西沙星治疗,对照组应用左氧氟沙星治疗,观察其临床效果和安全性。结果治疗组及对照组总有效率分别是80.8%和58.0%,痊愈率分别为50.0%和32.0%,两组共分离出细菌121株,细菌清除率分别为80.3%和58.3%、不良反应发生率分别为3.9%和10.0%,差异均有统计学意义(P<0.05)。结论莫西沙星治疗恶性肿瘤合并HAP患者临床疗效较好,细菌清除率高、优于左氧氟沙星,临床使用安全。
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| 关 键 词： | 莫西沙星 左氧氟沙星 恶性肿瘤 医院获得性肺炎 |
Moxifloxacin in treatment of malignant tumor merged hospital-acquired pneumonia:observation on its curative effect |
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| WANG Wei-hua,ZHENG Yi-hua,ZHOU Ai-xin,LIN Xue-mei,MAO Juan-hua,LI Zhen-hua. Moxifloxacin in treatment of malignant tumor merged hospital-acquired pneumonia:observation on its curative effect[J]. Chinese Journal of Nosocomiology, 2011, 21(22): 4794-4796 |
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| Authors: | WANG Wei-hua ZHENG Yi-hua ZHOU Ai-xin LIN Xue-mei MAO Juan-hua LI Zhen-hua |
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| Affiliation: | (Jiangshan People′s Hospital,Jiangshan,Zhejiang 324100,China) |
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| Abstract: | OBJECTIVE To observe the clinical efficacy and safety of moxifloxacin in treatment of malignant tumor merged hospital acquired character pneumonia. METHODS A total of 102 example malignant tumor complicated with HAP were divided into the treatment group(52 examples) and the control group(50 examples) radomly.The treatment group applied moxifloxacin star treatment,the control group applied levofloxacin to treat,its clinical effect and the security were observed. RESULTS Two groups of total effectiveness resp... |
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| Keywords: | Moxifloxacin Levofloxacin Malignant tumor Hospital-acquired pneumonia |
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