| 生物膜特效清洗剂MatrixTM对呼吸机管路生物膜的清除效率评价 |
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| 引用本文： | 黄佩佳,刘岩,丁志平. 生物膜特效清洗剂MatrixTM对呼吸机管路生物膜的清除效率评价[J]. 中华医院感染学杂志, 2011, 21(22): 4759-4761 |
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| 作者姓名： | 黄佩佳 刘岩 丁志平 |
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| 作者单位： | 1. 解放军总医院南楼临床部呼吸科,北京,100853
2. 解放军总医院感染管理科,北京,100853 |
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| 摘 要： | 目的评价生物膜特效清洗剂MatrixTM对呼吸机管路生物膜的清除效率。方法建立呼吸机管路生物膜模型,使用生物膜特效清洗剂MatrixTM和含酶清洗剂,按照推荐使用浓度完成清洗步骤,用生物膜活菌计数法和ATP生物荧光法评价生物膜特效清洗剂MatrixTM的清洗效果。结果使用生物膜特效清洗剂MatrixTM对呼吸机管路生物膜细菌清除效率达100.00%,ATP生物荧光法检测ATP降低率为99.19%;含酶清洗剂对细菌清除效率为98.08%,ATP生物荧光法检测ATP减少率为90.47%。结论生物膜特效清洗剂MatrixTM比酶清洗剂更能有效去除呼吸管路内生物膜。
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| 关 键 词： | 生物膜特效清洗剂MatrixTM 含酶清洗剂 生物膜 呼吸管路 生物膜活菌计数法 ATP生物荧光法 |
Evaluation of clearance effect of biofiim remover MatrixTM against biofilm on inner surface of ventilator pipes |
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| HUANG Pei-jia,LIU Yan,DING Zhi-ping. Evaluation of clearance effect of biofiim remover MatrixTM against biofilm on inner surface of ventilator pipes[J]. Chinese Journal of Nosocomiology, 2011, 21(22): 4759-4761 |
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| Authors: | HUANG Pei-jia LIU Yan DING Zhi-ping |
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| Affiliation: | HUANG Pei-jia,LIU Yan,DING Zhi-ping(General Hospital of PLA,Beijing 100853,China) |
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| Abstract: | OBJECTIVE To evaluate the clearance effect of the biofilm remover MatrixTM against Pseudomonas aeruginosa biofilm on inner surface of ventilator pipes. METHODS The biofilm model on inner surface of tubes was formed,tubes were cleaned by the biofilm remover MatrixTM and enzymatic detergents.The cleaning effect of tubes was evaluated by the method of surviving bacterial counts and ATP bioluminescence assay. RESULTS The bacterial burden of tubes which was cleared by biofilm remover MatrixTM reduced 100.0%,and ... |
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| Keywords: | Biofilm remover MatrixTM Enzymatic detergent Biofilm Ventilator pipes Survival bacterial counts ATP bioluminescence assay |
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