新生儿重症监护病房侵入性操作与医院感染的相关研究

目的通过临床回顾性研究,探讨新生儿重症监护病房(NICU)侵入性操作与医院感染的相关性。方法查阅2009年12月-2010年10月NICU新生儿的病历,记录患儿所采用的侵入性操作种类、持续时间及其与医院感染发生的相关性。结果 1458例新生儿发生医院感染107例,感染率为7.34%;NICU医院感染以呼吸道感染最多,占51.40%;未使用、使用1种、使用≥2种侵入性操作的医院感染发生率分别为:0.57%、5.83%、8.78%,感染发生率呈依次增加的趋势,差异有统计学意义(P<0.01);留置尿管、肠内营养、机械通气、中心静脉置管,可以增加新生儿重症监护病房医院感染发生的危险性,且随其应用的时间不同,发生医院感染的危险性也不同。结论应用侵入性操作,可以增加NICU医院感染的发生率,在综合衡量患儿病情和治疗措施的同时,尽量减少使用过多的侵入性操作。

Relationship between invasive procedure and nosocomial infection in neonate ICU

OBJECTIVE To study the relation between medical interventions and nosocomial infection(NI) in neonate ICU by clinical retrospective study.METHODS We carefully consulted the medical records of the neonate who checked in hospital from Dec 2009 to Oct 2010.The medical interventions and their time that they were used were recorded,then the relativity of medical interventions and NI in neonate ICU were investigated.RESULTS Nosocomial infection were happened in 107 neonate,and the infection rates were 7.34%;respi...