| 经动脉超声导管印压检测犬梗死心肌硬度 |
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| 引用本文： | 邓辉胜,郭睿,黄晶,王志刚.经动脉超声导管印压检测犬梗死心肌硬度[J].中国医学影像技术,2011,27(4):657-660. |
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| 作者姓名： | 邓辉胜 郭睿 黄晶 王志刚 |
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| 作者单位： | 1. 重庆医科大学附属第一医院老年科,重庆,400016
2. 重庆医科大学超声影像学研究所,重庆,400010;重庆医科大学附属第二医院心内科,重庆,400010 |
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| 基金项目： | 国家自然科学基金(30371361、30430230)。 |
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| 摘 要： | 目的 探讨经动脉导管超声印压检测梗死心肌硬度的可行性,并观察其与心肌胶原含量和Ⅰ/Ⅲ型胶原比值的关系。方法 将18只犬随机分为心肌梗死组(n=9)及假手术组(n=9),通过股动脉或颈动脉途径插管,将7F超声印压导管送入左心室,印压测量左心室前壁和心尖部硬度,并测量相应区域心肌胶原容积分数(CVF)、积分光密度(IOD)和Ⅰ、Ⅲ型胶原CVF比值(CVFⅠ/CVFⅢ)。结果 心肌梗死组前壁、心尖部心肌硬度值分别为(140.69±30.71)kPa、(49.08±6.17)kPa,均显著高于假手术组 。两组犬前壁心肌应力和相关形变均呈线性关系(心肌梗死组Y=138.17X,r=0.90,假手术组Y=18.69X,r=0.84,P均<0.05)。梗死组前壁、心尖部心肌CVF、IOD、CVFⅠ/CVFⅢ与假手术组相比均显著升高(P均<0.05)。结论 介入超声印压能够区分活体犬梗死心肌与正常心肌之间的硬度差异。
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| 关 键 词： | 狗 心肌梗死 介入超声印压 心肌硬度 |
| 收稿时间： | 2010/11/29 0:00:00 |
| 修稿时间： | 2010/12/25 0:00:00 |
Trans-arterial stiffness assessment on myocardial infarction in canine with ultrasound indentation catheter |
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| DENG Hui-sheng,GUO Rui,HUANG Jing and WANG Zhi-gang.Trans-arterial stiffness assessment on myocardial infarction in canine with ultrasound indentation catheter[J].Chinese Journal of Medical Imaging Technology,2011,27(4):657-660. |
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| Authors: | DENG Hui-sheng GUO Rui HUANG Jing and WANG Zhi-gang |
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| Institution: | Department of Geriatrics, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China;Institute of Ultrasonic Imaging, Chongqing Medical University, Chongqing 400010, China;Department of Cardiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China;Institute of Ultrasonic Imaging, Chongqing Medical University, Chongqing 400010, China;Department of Cardiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China;Institute of Ultrasonic Imaging, Chongqing Medical University, Chongqing 400010, China;Department of Cardiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China |
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| Abstract: | |
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| Keywords: | Dogs Myocardial infarction Interventional ultrasound indentation Myocardial stiffness |
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