Secondary hyperparathyroidism as a palpable intrathyroid parathyroid gland in a patient with hypophosphatemic osteomalacia |
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| Authors: | Deng-Huang Su Kuo-Meng Liao Ying-Chun Chang Keh-Sung Tsai |
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| Institution: | (1) Department of Internal Medicine, Far Eastern Polyclinic, Taipei, Taiwan;(2) Department of Internal Medicine, Zhongxiao Branch, Taipei City Hospital, Taipei, and Chung-Hsiao Municipal Hospital, Taipei, Taiwan;(3) Department of Internal Medicine, Miao-Li General Hospital, Department of Health, Executive Yuan, Miao-Li, Taiwan;(4) Department of Laboratory, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7 Chung-Shan South Road, Taipei, 100, Taiwan |
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| Abstract: | Secondary hyperparathyroidism is sometimes seen in patients with hypophosphatemic osteomalacia after long-term oral phosphate
therapy. Parathyroidectomy is sometimes needed for the correction of hypercalcemia in these patients, and is rarely performed
in patients without hypercalcemia. A 46-year-old female patient had hypophosphatemic osteomalacia with unknown cause and secondary
hyperparathyroidism. A palpable neck mass developed after long-term oral phosphate therapy. An intrathyroid parathyroid gland
was confirmed through partial thyroidectomy and parathyroidectomy. Renal phosphate wasting decreased strongly, and serum parathyroid
hormone was in the normal range after the operation. A correction of secondary hyperparathyroidism may partially overcome
hyperphosphaturia in some patients with hypophosphatemic rickets. |
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| Keywords: | hyperparathyroidism hypophosphatemia osteomalacia |
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