| p62dok—PTB结构域样新基因片段的克隆 |
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| 引用本文： | 张勇,周明明.p62dok—PTB结构域样新基因片段的克隆[J].中国神经科学杂志,2000,16(2):164-165. |
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| 作者姓名： | 张勇 周明明 |
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| 基金项目： | 国家重点基础研究规划“脑功能和脑重大疾病的基础研究”资助项目!( G19990 5 40 0 0 ) |
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| 摘 要： | 利用ＲＴ－ＰＣＲ方法，从胎儿脾脏和肝脏组织中克隆出一个３４２ｂｐ的基因片段，并测定了其核苷酸序列。在基因库中未见相同序列报道，但该片段与ｐ６２ｄｏｋ－ＰＴＢ结构域苷酸序列有９３％的同源性，提示它是一种新的ｐ６２ｄｏｋ－ＰＴＢ域样基因片段。
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| 关 键 词： | p62dok PTB结构域 基因片段 克隆 |
Cloning of a novel gene fragment related to p62dok-PTB domain |
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| ZHANG Yong ,CHEN Zhe yu ,HUANG Ai jun ,LU Chang lin ,ZHOU Ming ming ,HE Cheng.Cloning of a novel gene fragment related to p62dok-PTB domain[J].Neuroscience Bulletin,2000,16(2):164-165. |
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| Authors: | ZHANG Yong CHEN Zhe yu HUANG Ai jun LU Chang lin ZHOU Ming ming HE Cheng |
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| Institution: | ZHANG Yong 1,CHEN Zhe yu 1,HUANG Ai jun 1,LU Chang lin 1,ZHOU Ming ming 2,HE Cheng 1 |
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| Abstract: | A 342bp gene fragment was cloned from human fetal spleen and liver tissues by RT PCR.It has been sequenced and no identical sequence was found in Genebank.However,the homogeneity between the gene fragment and p62dok PTB domain gene was about 93%.This result suggested it is a novel gene fragment related to p62dok PTB domain. |
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| Keywords: | p62dok PCR PTB domain receptor tyrosine kinases |
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